Scientific Programme and Abstracts

Nottingham 2011 meeting abstracts can be viewed by clicking the Paper or Poster underlined.

Selected Powerpoint presentations of abstracts can also be downloaded from the Members' Area.  Please click here.

Wednesday 22nd June 2011: Pre-meeting

 

 

08.30-13.00

 

Experimental Hydrocephalus [Hazel Jones].

click here to view abstracts

Clinical Case Studies [Roger Strachan].

click here to view abstracts

14.00

14.30

Executive Committee Meeting (Newark Hall)

Registration (Exchange building)

17.00

Annual General Meeting (AGM) for members only. (Room C49 - Dearing Building)

19.30

Welcome Reception: Nottingham Council House

Thursday 23rd June 2011: Main Programme and Abstracts

08.45

 

Introduction: Welcome to Nottingham:Professor Ian Hall, Dean of the Faculty of Medicine and Health Sciences.

09.00-10.30

 

Scientific Session 1: Hydrocephalus and shunt surgery

Chaired by: Roger Strachan and Jackie Reaper

09.00

Paper1   

Contemporary Hydrocephalus Shunt Technology

Zofia Czosnyka, Marek Czosnyka, Hugh K Richards, John D Pickard

Addenbrooke's Hospital, Cambridge

09.15

Paper 2

Use of neuro-navigation for inserting both the proximal and distal catheters for ventriculo-atrial shunts

Bahl A, McMullan J

§ Hallamshire Hospital, Sheffield

09.30

Paper 3

Suprahepatic placement of ventriculoperitoneal shunt - a safe haven in cases of recurrent abdominal end blockage

Janini Krishnan, Santosh Karmarkar

Lilavati Hospital, Mumbai

09.45

Paper 4

Comparison of the endoscopic third ventriculostomy and ventriculo-peritoneal shunt at the treatment of patients with normal pressure hydrocephalus

Fernando Campos Gomes Pinto, Fernanda Letkaske, Juliana Tornai, Maria Izabel Romao, Juliana Brasileiro Queiroz, Emilia Aparecida Valinetti, Melissa Castello Branco e Silva, Felipe Saad, Ricardo Luis Barbosa, Manoel Jacobsen Teixeira

Sao Paulo, Brazil

10.00

Paper 5

ETV vs shunt: a randomised trial comparing endoscopic third ventriculostomy versus shunt revision for shunt malfunction

Roddy O'Kane, Darach Crimmins, Paul Chumas,Atul Tyagi, John Goodden

Leeds General Infirmary, Leeds, UK

10.15

Paper 6

Early diagnosis of a human foetus undergoing a progressive obliteration of Sylvius Aqueduct and hydrocephalus allowed a prompt and successful postnatal surgery. A case report.

Eduardo Ortega, Francisco Guerra, Rosa I Munoz, Karin Vio, Montserrat Guerra, Jaime Jaque, Federico Batiz, Sara Rodriguez, Esteban Rodriguez

Universidad Austral de Chile & University of Magdeburg, Germany

10.30

 

Coffee/tea

11.00 -11.45

 

Special lecture: Dr Jocelyn Glazier, University of Manchester

Folate-homocysteine interactions: a placental perspective

Introduced by Roger Bayston

click here to view abstract

 

 

11.45-12.45

 

Scientific Session 2:  Factors in causation of Neural Tube Defects

Chaired by: Ian Pople and Gill Yaz

11.45

Paper 7

Environmental factors and anterior encephaloceles in Assamese tea garden workers: a preliminary survey

Hemonta Kr. Dutta

Assam Medical College, India

12.00

Paper 8

 

Persistent elevated NTD rates in Ukraine - Highest in Chornobyl Impacted Regions

Wladimir Wertelecki, Lyubov Yevtushok, Natalia Zymak-Zakutnya, Serhiy Lapchenko, Natalia Yuskiv

Rivne, Ukraine

 

12.15

Paper 9

The PONTI clinical trial - Prevention of Neural Tube Defects by Inositol - an update on progress

Andrew Copp, Victoria Shepherd, Lyn Chitty, Nicholas Greene

Institute of Child Health & University College London

12.30

Paper 10

Update on folic acid from the Society Folic Acid Spokesperson

Carole Sobkowiak

 

12.45

End

Lunch - Catering Atrium

Thursday afternoon and evening: Society Outing

 

Friday 24th June 2011: Main Programme and Abstracts

08.30-10.30

 

Scientific Session 3: Spina bifida and urology

Chaired by: Pieter Dik and Reinhold Cremer

08.30

Paper 11

 

"Survival of the fittest" in open spina bifida: 40 year cohort study

Pippa Oakeshott, Gillian M Hunt, Alison Poulton, Fiona Reid

Universities of London, Sydney and Cambridge.

08.45

Paper 12

Botulinum toxin in the treatment of incontinence in children with neurogenic bladder dysfunction 

Sven Mattsson, Gunilla Glad Mattsson, Anders Spangberg

University Hospital, Linköping, Sweden

09.00

Paper 13

The role of abdominal stomas in the management of bowel and bladder incontinence in cases of spina bifida 

Janani Krishnan, Santosh Karmarkar

Lilavati Hospital, Mumbai

09.15

Paper 14

Diffusion tensor MRI and tractography of the sacral plexus and its branching nerves; feasibility and initial results 

Pasquelle K.N. van der Jagt, Alexander Leemans, Martijn Froeling, Thomas C Kwee, Rutger A.j. Nievelstein, Bennie ten Haken, Pieter Dik

Universities of Twente, Utrecht, Eindhoven & Amsterdam

09.30

Paper 15

The impact of the management of the neuropathic bladder and long term outcomes in spina bifida patients 

Georgina Malakounides, Ray Hsu, Frank Lee, Feilim Murphy, Su-Anna Boddy

St George's Hospital, London

09.45

Paper 16

Digital Muscle-Ultrasound Parameters Reveal Muscle Impairment in Spina Bifida Aperta with Lumbar Myelomeningocele after the First Year of Life 

Renate j Verbeek, Natalia Maurits, Oebele F. Brouwer, Johannes H. van der Hoeven, Deborah A. Sival

University of Groningen, Netherlands

 

10.00

Paper 17

In Spina Bifida Aperta, Visual Assessment of Muscle Ultrasound Density Can Reveal Muscle Damage 

R Brandsma, R.j. Verbeek, JTH Hamminga, NM Maurits, AL Staal-Schreinemacher, OF Brouwer, JH van der Hoeven, DA Sival

University of Groningen, Netherlands

10.15

Paper 18

New prospect of treatment on the immediate post-myelomeningocele repair applying low level laser therapy in newborn

Fernando Campos Gomes Pinto, Maria Cristina Chavantes, Nathali Cordeiro Pinto, Eduardo Alho, Elisabeth Yoshimura, Hamilton Matushita, Vera Krebs, Manoel Jacobsen Teixeira

Sao Paulo, Brazil

10.30

Coffee/tea

 

 11.00-12.55

 11.00-11.15

Session 4: Prenatal treatment of NTD

Special guest: Professor Peter Morris, MRI expert, co-worker with Sir Peter Mansfield

Introduced by Professor Paul Griffiths

Special Session: Casey Holter Lecture

Introduced by Roger Bayston

Chaired by: Paul Griffiths and Professor Peter Morris

11.15 - 12.00

 

Casey Holter Lecture 2011

"Prenatal counselling: setting the standards"

Maria Cartmill, Neurosurgeon, Queen's Medical Centre, Nottingham

click here to view abstract

12.00-12.15

Paper 19

Need for postnatal neurosurgical interventions after intrauterine telescopic myelomeningocele repair

Reinhold Cremer, Martina Messing-Junger

Cologne Children's Hospital & Asklepios Klinik, St Augustin, Germany

12.15-12.45

 

Special Lecture

Perspective for the MOMS study

David Shurtleff

Seattle, USA

click here to view abstract

12.45-

12.55

12.55-14.00

 

General discussion and questions

 

Lunch - Catering Atrium

14.00-15.30

 

Scientific Session 5: Experimental Hydrocephalus

Chaired by: Deborah Sival and Kalyan Raman

14.00

Paper 20

Agenesis of the corpus collosum as a consequence of a defect of the program of development in the neuroepithelium in the hydrocephalic hyh mouse

Luis Manuel Rodriguez-Perez, Patricia Paez, Isabel de Diego, Ruth Roales-Bujan, Anibal Smith, Pedro Fernandez-Liebrez, Jose Manuel Perez-Figares, Antonio J Jiminez

University of Malaga, Spain

14.15

Paper 21

Arterial hypertension effects on the cerebral flow and the accumulation of beta-amyloid in the choroid plexus

Augustin Castaneyra-Perdoma, Antonio Alayon, Ibrahim Gonzalez-Marrero, Juan m Gonzalez-Toledo, Leandro Castaneyra-Ruiz, Hector de Paz-Carmona, Rafale Castro, Liberto Brage, Agustin Castaneyra-Ruiz, Emilia M Carmona-Calero

University of Tenerife, Spain

14.30

Paper 22

Origin and role of the astrocytic periventricular reaction in foetal onset hydrocephalus

Immaculada Ruz-Maldonado, Ruth Roales-Bujan, Patricia Paez, Luis M Rodriguez-Perez, Maria-Dolores Dominguez-Pinos, Maria Martinez-Leon, Montserrat Guerra, Sara Rodriguez, Manuell-Pedro Jiminez-Garcia, Ailec Ho-Plagaro, Miguel-Angel Gonzalez-Porras, Maria Garcia-Bonilla, Jesus M Grondona, Esteban M Rodriguez, Jose-Manuel Perez-Figares, Antonio J Jiminez

University of Malaga, Spain

14.45

Paper 23

Effects of ventricular reservoir timing and CSF tapping in experimental neonatal hydrocephalus

James P [Pat] McAllister, Ramin Eskandari, Osama Abdullah, Melissa Packer, Kelley Deren, Chase Bryan, Eric Burdett

University of Utah, USA

15.00

Paper 24

Effects of experimental communicating hydrocephalus on neocortical capillary flow pulsatility

Mark Wagshul, Shams Rashid, Yiting Yu, James P [Pat] McAllister

Albert Einstein College of Medicine, New York, Stoney Brook University, New York, and University of Utah, USA

15.15

Paper 25

Induction of neurospheres from rat embryonic stem cells by conditioned medium with embryonic cerebrospinal fluid

Siamak Yari, Kazem Parivar, Mohammad Nabiuni, Mohammad Keramatipour, Majid Rajabi

Tarbiat Moallem University, Tehran, Iran

PAPER CANCELLED

15.30

 

Coffee/tea

15.45 - 16.30

 

Session 6: Poster Viewing: Moderator: Hugh Richards 

 

Poster 1

The choroid plexuses and subcommissural organ. Immunohistochemical study in the human embryonic brain and hydrocephalus

Emilia M Carmona-Calero, Juan M Gonzalez-Toledo, Ibrahim Gonzalez-Marrero, Augustin Castaneyra-Ruiz, Hector de Paz-Carmona, Leandro Castaneyra-Ruiz, Isabel Hernandez-Garde, Agustin Castaneyro-Perdomo

Universidad de la Laguna, Tenerife & Fuerteventura, Spain

 

Poster 2

Mutations of VANGL2 gene in human neural tube defects

Valeria Capra, Patrizia De Marco, Elisa Merello, Sandra Salem, Ciprian Bosoi, E Pauwels, Gianluca Piatelli, Armando Cama, Alexander Bassuk, Zoha Kibar

Istituto G Gaslini, Genoa, Italy, & Quebec, Montreal and Iowa

POSTER CANCELLED

 

Poster 3

Vascular density changes in the frontal cortex of an experimental model of chronic hydrocephalus

Abhishek Deshpande, Stephen M Dombrowski, Natalie Krajcir, Jun Yang, Debbie Schmidt, Mark G Luciano

Cleveland Clinic, Ohio, USA

POSTER CANCELLED

 

Poster 4

Tissue responses in porcine brains due to long-term implantation of subdural and intraparenchymal telemetric ICP measurement devices

Sebastian Antes, Regina Eymann, Melanie Schmitt, Yoo-Jin Kim, Rainer M Bohle, Michael Kiefer

Saarland University, Homburg -Saar, Germany

 

Poster 5

Telemetric ICP measurements to detect hidden hydrocephalus behind Chiari 1 malformation

Melanie Schmitt, Michael Kiefer, Sebastian Antes, Regina Eyman

Saarland University, Homburg -Saar, Germany

 

Poster 6

Different manifestations of Chiari 1 malformation within 3 families

Melanie Schmitt, Michael Kiefer, Sebastian Antes, Regina Eyman

Saarland University, Homburg -Saar, Germany

 

Poster 7

Endoscopic third ventriculostomy as an efficient treatment of hydromyelia

Mikkel Mylius Rasmussen, Dorte Clemmensen, Cerasela Slimac, Torben Skovbo Hansen, Michael Pedersen

University Hospital, Aarhus, Denmark

 

Poster 8

Preoperative prognostic factors affecting outcome following untethering for symptomatic spina bifida occulta in 31 patients

Jen-Ho Tseng, Ming-Yuan Tseng

Taipei City Hospitals, Taiwan & Nottingham University Hospitals, UK

POSTER CANCELLED

 

Poster 9

Physeal injury mimicking osteomyelitis in a patient with spina bifida - case report and review of the literature

Marcus Pauly, Gerd Horneff, Bernd Weber, Michael Szallies, Ulrike Brokmeier

Asklepios Children's Hospital, Germany

 

 

Poster 10

Suprapubic "button" cystostomy as an alternative method of bladder access in selected cases of children with neurogenic bladder and congenital malformations?

Marcus Pauly, Thomas Riedel, Ulrike Brokmeier, Wolfram Kluwe

Asklepios Children's Hospital, Germany

 

 

Poster 11

The role of intracranial pressure monitoring in the investigation of suspected shunt malfunction

Jacqueline Reaper, Sally Ann Collins, Jamie Robins, John McMullan

Royal Hallamshire Hospital, Sheffield, UK

 

Poster 12

Burns by a laptop-accumulator in a child with spina bifida

Reinhold Cremer

Children's Hospital, Cologne, Germany

 

Poster 13

Navigational abilities of individuals with hydrocephalus - a pilot study

Matthew G Buckley, Alastair D Smith

University of Nottingham, UK

 

 

 

16.30-18.00

 

Scientific Session 7: Intracranial pressure management: complications

Chaired by: Michael Pollay and Pat McAllister

 

16.30

Paper 26

Clinical utility of radionuclide shuntography in assessing shunt function undefined by other imaging studies

Ming-Yuan Tseng, Jen-Ho Tseng

Nottingham University Hospitals, UK & Taipei City Hospitals, Taiwan

16.45

Paper 27

Diffusion tensor imaging before and after shunting in mild experimental hydrocephalus

Weihong Yuan, Francesco Mangano, Pat McAllister, Diana Lindquist, Scott Dunn

Cincinnati Children's Hospital & University of Utah, USA

17.00

Paper 28

The action of linezolid and linezolid-rifampicin combination on biofilm in ventriculo-peritoneal shunts, an in vitro study

Gautham Ullas, Roger Bayston, Waheed Ashraf

University of Nottingham, UK

17.15

Paper 29

The reference pressure controversy in the Marmarou model

Kalyan Raman

Northwestern University, Illinois, USA

 

17.30

Paper 30

Does the use of antimicrobial external ventricular drainage catheters increase bacterial resistance?

Waheed Ashraf, Roger Bayston, Oxana Stevenson, Gagori Bandopadhyay, Arooj Justin

University of Nottingham, UK

17.45

Paper 31

Antibiotic impregnated shunt catheter: a metaanalysis

Michael Kiefer, Melanie Schmitt, Sebastian Antes, Regina Eymann

Saarland University, Homburg -Saar, Germany

18.00

 

End

19.30

 

Society Dinner: Old Library, Nottingham Trent University

Saturday 25th June 2011: Main Programme

09.00-10.30

Scientific Session 8: Current Issues

Chaired by: Carole Sobkowiak and Sven Mattsson

09.00

Paper 32

Localisation and identification of bacteria in the skin of patients after skin preparation

Lauren Glen, Nuruljannah Ismail, Waheed Ashraf, Brigitte Scammell, Roger Bayston

University of Nottingham, UK

09.15

Paper 33

Paediatric neurosurgery for spina bifida in the Republic of Ireland: a retrospective audit of postoperative infection

Karen Burns, John Caird, David Allcutt, Mohammed Sattar, Darach Crimmins, Patrick Gavin, Karina Butler, Mary Cafferkey, Robert Cunney

Children's University Hospital, Dublin

09.30

Paper 34

Stridor presenting at birth predicts poor outcome in neonates with myelomeningocele

Eylem Ocal, Shibu Pillai, Bev Irwin, Ash Singhal, Douglas D Cochrane, Paul Steinbok

Children's Hospital British Columbia, Canada

PAPER CANCELLED

09.45

Paper 35

Assessing and addressing self-awareness of neuropsychological function in individuals with hydrocephalus

Catherine Loveday, Joanna Iddon, Trudi Edginton, John Pickard, Richard Morgan

University of Westminster, London; Chelsea & Westminster Hospital, London; & Addenbrooke's Hospital, Cambridge

10.05

Paper 36

Functional outcome of children at school-age with post-haemorrhagic hydrocephalus

Janyte Holwerda, Koenraad NJA van Braeckel, Elise Roze, Eeico W Hoving, Albert Martijn, Carel GB Maathuis, Oebele F Brouwer, Arend F Bos

University Medical Centre, Groningen, Netherlands

10.20

  Paper 37

High dose folic acid as myelomeningocele prophylactics - time for a change in recommendations?

Mikkel Mylius Rasmussen, Mathias Thygesen, Dorte Clemmensen, Morten Fenger-Green, Olav B Petersen, Claus Mosdal

Aarhus University Hospital, Denmark

10.35

 

Coffee/tea

11.00-12.45

Scientific Session 9: The Cerebrospinal Fluid Environment

Chaired by: Dorte Clemmensen and Waheed Ashraf

11.00

Paper 38

A new neuroendoscopic technique to prevent recurrent obstructions of the CSF pathway

Michael Kiefer, Melanie Schmitt, Sebastian Antes, Panagiotis Papanagiotou, Regina Eymann

Saarland University, Homburg -Saar, Germany

11.15

Paper 39

Analysis of cerebrospinal fluid from human neonates with fluid problems associated with different neurological conditions

Irum Naureen, Besma Nash, Shahid Chohan, Khawaja Waheed, Conor Mallucci, Sasha Burn, Dawn Williams, John Godden, Suresh Victor, Jaleel Miyan

University of Manchester, UK; Islamabad, Pakistan; Lahore, Pakistan; Alder Hey Children's Hospital, Liverpool & St Mary's Hospital Manchester, UK.

PAPER CANCELLED

11.30

Paper 40

In human hydrocephalic foetus and Htx rats neural precursor cells are displaced from the subventricular zone to the ventricle and can be collected from the cerebrospinal fluid

Esteban Rodriguez, Alexander Ortloff, Karin Vio, Cesar Gonzalez, Montserrat Guerra, Rosa I Munoz, Eduardo Ortega, Jaime Jaque, Francisco Guerra, Luis Federico Batiz, Sara Rodriguez

Universidad Austral de Chile, Chile.

11.45

Paper 41

Is there an immune response associated to the onset of neuroepithelium/ependyma disruption that leads to congenital hydrocephalus?

Montserrat Guerra, Alexander Ortloff, Karin Vio, Rosa I Munoz, Eduardo Ortega, Jaime Jaque, Francisco Guerra, Thilo Kahne, Federico Batiz, Sara Rodriguez, Esteban M Rodriguez

Universidad Austral de Chile, Chile.

12.00

Paper 42

Stem cell research in severe type of L1CAM syndrome [X-linked hydrocephalus]

Yamasaki M, Shofuda T, Bamba Y, Yoshioka E, Nonaka M, Kanemura Y.

Japan

12.15

Paper 43

In newborn spina bifida aperta, diffuse cerebral white-and-grey-matter swelling precedes onset of high pressure hydrocephalus

Deborah A Sival, Eelco W Hoving, Oebele F Brouwer, Linda C Meiners

University of Groningen, Netherlands

12.30

 

Closing remarks

12.45

Invitation to The Netherlands 2012: Pieter Dik

 

 

13.00

Finish. Packed lunch provided.

 

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